Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015
Identifieur interne : 002B63 ( Main/Exploration ); précédent : 002B62; suivant : 002B64Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015
Auteurs : S. Gillessen [Suisse] ; A. Omlin [Suisse] ; G. Attard [Royaume-Uni] ; J. S. De Bono [Royaume-Uni] ; E. Efstathiou [États-Unis, Grèce] ; K. Fizazi [France] ; S. Halabi ; P. S. Nelson ; O. Sartor ; M. R. Smith ; H. R. Soule [États-Unis] ; H. Akaza [Japon] ; T. M. Beer ; H. Beltran ; A. M. Chinnaiyan [États-Unis] ; G. Daugaard [Danemark] ; I. D. Davis [Australie] ; M. De Santis [Royaume-Uni, Autriche] ; C. G. Drake [États-Unis] ; R. A. Eeles [Royaume-Uni] ; S. Fanti [Italie] ; M. E. Gleave [Canada] ; A. Heidenreich [Allemagne] ; M. Hussain [États-Unis] ; N. D. James [Royaume-Uni] ; F. E. Lecouvet [Belgique] ; C. J. Logothetis [États-Unis] ; K. Mastris [Royaume-Uni] ; S. Nilsson [Suède] ; W. K. Oh [États-Unis] ; D. Olmos ; A. R. Padhani ; C. Parker [Royaume-Uni] ; M. A. Rubin [États-Unis] ; J. A. Schalken [Pays-Bas] ; H. I. Scher ; A. Sella [Israël] ; N. D. Shore ; E. J. Small [États-Unis] ; C. N. Sternberg [Italie] ; H. Suzuki [Japon] ; C. J. Sweeney [États-Unis] ; I. F. Tannock [Canada] ; B. Tombal [Belgique]Source :
- Annals of Oncology [ 0923-7534 ] ; 2015.
Descripteurs français
- KwdFr :
- Adénocarcinome (), Adénocarcinome (anatomopathologie), Agents de maintien de la densité osseuse (usage thérapeutique), Antagonistes des androgènes (usage thérapeutique), Antinéoplasiques (usage thérapeutique), Antinéoplasiques hormonaux (usage thérapeutique), Guides de bonnes pratiques cliniques comme sujet, Humains, Mâle, Orchidectomie, Prostatectomie, Radiothérapie adjuvante, Taxoïdes (usage thérapeutique), Tumeurs de la prostate (), Tumeurs de la prostate (anatomopathologie), Tumeurs prostatiques résistantes à la castration (), Tumeurs prostatiques résistantes à la castration (anatomopathologie).
- MESH :
- anatomopathologie : Adénocarcinome, Tumeurs de la prostate, Tumeurs prostatiques résistantes à la castration.
- usage thérapeutique : Agents de maintien de la densité osseuse, Antagonistes des androgènes, Antinéoplasiques, Antinéoplasiques hormonaux, Taxoïdes.
- Adénocarcinome, Guides de bonnes pratiques cliniques comme sujet, Humains, Mâle, Orchidectomie, Prostatectomie, Radiothérapie adjuvante, Tumeurs de la prostate, Tumeurs prostatiques résistantes à la castration.
English descriptors
- KwdEn :
- Adenocarcinoma (pathology), Adenocarcinoma (therapy), Androgen Antagonists (therapeutic use), Antineoplastic Agents (therapeutic use), Antineoplastic Agents, Hormonal (therapeutic use), Bone Density Conservation Agents (therapeutic use), Humans, Male, Orchiectomy, Practice Guidelines as Topic, Prostatectomy, Prostatic Neoplasms (pathology), Prostatic Neoplasms (therapy), Prostatic Neoplasms, Castration-Resistant (pathology), Prostatic Neoplasms, Castration-Resistant (therapy), Radiotherapy, Adjuvant, Taxoids (therapeutic use).
- MESH :
- chemical , therapeutic use : Androgen Antagonists, Antineoplastic Agents, Antineoplastic Agents, Hormonal, Bone Density Conservation Agents, Taxoids.
- pathology : Adenocarcinoma, Prostatic Neoplasms, Prostatic Neoplasms, Castration-Resistant.
- therapy : Adenocarcinoma, Prostatic Neoplasms, Prostatic Neoplasms, Castration-Resistant.
- Humans, Male, Orchiectomy, Practice Guidelines as Topic, Prostatectomy, Radiotherapy, Adjuvant.
Abstract
The first St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) Expert Panel identified and reviewed available evidence for the ten most important areas of controversy in advanced prostate cancer management. Recommendations based on expert opinion are presented. Detailed decisions on treatment will involve clinical consideration of disease extent and location, prior treatments, host factors, patient preferences and logistical and economic constraints.
Url:
DOI: 10.1093/annonc/mdv257
PubMed: 26041764
PubMed Central: 4511225
Affiliations:
- Allemagne, Australie, Autriche, Belgique, Canada, Danemark, France, Grèce, Israël, Italie, Japon, Pays-Bas, Royaume-Uni, Suisse, Suède, États-Unis
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Le document en format XML
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Omlin</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af1"><addr-line>Department of Oncology/Haematology</addr-line>,<institution>Kantonsspital St Gallen</institution>,<addr-line>St Gallen</addr-line>,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Attard, G" sort="Attard, G" uniqKey="Attard G" first="G." last="Attard">G. Attard</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af2"><addr-line>Prostate Cancer Targeted Therapy Group and Drug Development Unit</addr-line>,<institution>The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research</institution>,<addr-line>Sutton</addr-line>,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="De Bono, J S" sort="De Bono, J S" uniqKey="De Bono J" first="J. S." last="De Bono">J. S. 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Anderson Cancer Centre</institution>,<addr-line>Houston</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="mdv257_af5"><addr-line>Department of Clinical Therapeutics</addr-line>,<institution>Alexandra Hospital, National and Kapodistrian University of Athens Medical School</institution>,<addr-line>Athens</addr-line>,<country>Greece</country></nlm:aff><country xml:lang="fr">Grèce</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Fizazi, K" sort="Fizazi, K" uniqKey="Fizazi K" first="K." last="Fizazi">K. Fizazi</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af6"><addr-line>Department of Cancer Medicine, Institut Gustave Roussy</addr-line>,<institution>University of Paris Sud</institution>,<addr-line>Villejuif</addr-line>,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Halabi, S" sort="Halabi, S" uniqKey="Halabi S" first="S." last="Halabi">S. Halabi</name><affiliation><nlm:aff id="mdv257_af7"><addr-line>Department of Biostatistics and Bioinformatics</addr-line>,<institution>Duke University</institution>,<addr-line>Durham</addr-line></nlm:aff></affiliation></author><author><name sortKey="Nelson, P S" sort="Nelson, P S" uniqKey="Nelson P" first="P. S." last="Nelson">P. S. Nelson</name><affiliation><nlm:aff id="mdv257_af8"><addr-line>Division of Human Biology</addr-line>,<institution>Fred Hutchinson Cancer Research Centre</institution>,<addr-line>Seattle</addr-line></nlm:aff></affiliation></author><author><name sortKey="Sartor, O" sort="Sartor, O" uniqKey="Sartor O" first="O." last="Sartor">O. Sartor</name><affiliation><nlm:aff id="mdv257_af9"><addr-line>Tulane Cancer Centre</addr-line>,<institution>Tulane University</institution>,<addr-line>New Orleans</addr-line></nlm:aff></affiliation></author><author><name sortKey="Smith, M R" sort="Smith, M R" uniqKey="Smith M" first="M. R." last="Smith">M. R. Smith</name><affiliation><nlm:aff id="mdv257_af10"><institution>Massachusetts General Hospital Cancer Centre</institution>,<addr-line>Boston</addr-line></nlm:aff></affiliation></author><author><name sortKey="Soule, H R" sort="Soule, H R" uniqKey="Soule H" first="H. R." last="Soule">H. R. Soule</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af11"><institution>Prostate Cancer Foundation</institution>,<addr-line>Santa Monica</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Akaza, H" sort="Akaza, H" uniqKey="Akaza H" first="H." last="Akaza">H. Akaza</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af12"><addr-line>Research Centre for Advanced Science and Technology</addr-line>,<institution>The University of Tokyo</institution>,<addr-line>Tokyo</addr-line>,<country>Japan</country></nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Beer, T M" sort="Beer, T M" uniqKey="Beer T" first="T. M." last="Beer">T. M. Beer</name><affiliation><nlm:aff id="mdv257_af13"><institution>Oregon Health & Science University Knight Cancer Institute</institution>,<addr-line>Portland</addr-line></nlm:aff></affiliation></author><author><name sortKey="Beltran, H" sort="Beltran, H" uniqKey="Beltran H" first="H." last="Beltran">H. Beltran</name><affiliation><nlm:aff id="mdv257_af14"><addr-line>Department of Medicine</addr-line>,<institution>Weill Cornell Medical College</institution>,<addr-line>New York</addr-line></nlm:aff></affiliation></author><author><name sortKey="Chinnaiyan, A M" sort="Chinnaiyan, A M" uniqKey="Chinnaiyan A" first="A. M." last="Chinnaiyan">A. M. Chinnaiyan</name><affiliation><nlm:aff id="mdv257_af15"><addr-line>Michigan Centre for Translational Pathology, Department of Pathology</addr-line></nlm:aff><wicri:noCountry code="subfield">Department of Pathology</wicri:noCountry></affiliation><affiliation><nlm:aff id="mdv257_af16"><addr-line>Department of Urology, Comprehensive Cancer Centre</addr-line></nlm:aff><wicri:noCountry code="subfield">Comprehensive Cancer Centre</wicri:noCountry></affiliation><affiliation wicri:level="1"><nlm:aff id="mdv257_af17"><addr-line>Howard Hughes Medical Institute</addr-line>,<institution>University of Michigan Medical School</institution>,<addr-line>Ann Arbor</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Daugaard, G" sort="Daugaard, G" uniqKey="Daugaard G" first="G." last="Daugaard">G. Daugaard</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af18"><addr-line>Department of Oncology</addr-line>,<institution>Copenhagen University Hospital, Rigshospitalet</institution>,<addr-line>Copenhagen</addr-line>,<country>Denmark</country></nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Davis, I D" sort="Davis, I D" uniqKey="Davis I" first="I. D." last="Davis">I. D. Davis</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af19"><addr-line>Monash University and Eastern Health</addr-line>,<institution>Eastern Health Clinical School</institution>,<addr-line>Box Hill</addr-line>,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="De Santis, M" sort="De Santis, M" uniqKey="De Santis M" first="M." last="De Santis">M. De Santis</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af20"><addr-line>Cancer Research Centre</addr-line>,<institution>University of Warwick</institution>,<addr-line>Warwick</addr-line>,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="mdv257_af21"><institution>Ludwig Boltzmann Institute for Applied Cancer Research, Kaiser Franz Josef-Spital</institution>,<addr-line>Vienna</addr-line>,<country>Austria</country></nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Drake, C G" sort="Drake, C G" uniqKey="Drake C" first="C. G." last="Drake">C. G. Drake</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af22"><addr-line>Johns Hopkins Sidney Kimmel Cancer Center and The Brady Urological Institute, Department of Urology</addr-line>,<institution>Johns Hopkins University School of Medicine</institution>,<addr-line>Baltimore</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Eeles, R A" sort="Eeles, R A" uniqKey="Eeles R" first="R. A." last="Eeles">R. A. Eeles</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af23"><institution>The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust</institution>,<addr-line>London</addr-line>,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Fanti, S" sort="Fanti, S" uniqKey="Fanti S" first="S." last="Fanti">S. Fanti</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af24"><addr-line>Department of Nuclear Medicine, Policlinico S. Orsola</addr-line>,<institution>University of Bologna</institution>,<addr-line>Bologna</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gleave, M E" sort="Gleave, M E" uniqKey="Gleave M" first="M. E." last="Gleave">M. E. Gleave</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af25"><addr-line>Urological Sciences, Vancouver Prostate Centre</addr-line>,<institution>University of British Columbia</institution>,<addr-line>Vancouver</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Heidenreich, A" sort="Heidenreich, A" uniqKey="Heidenreich A" first="A." last="Heidenreich">A. Heidenreich</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af26"><addr-line>Klinik und Poliklinik für Urologie</addr-line>,<institution>RWTH University Aachen</institution>,<addr-line>Aachen</addr-line>,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hussain, M" sort="Hussain, M" uniqKey="Hussain M" first="M." last="Hussain">M. Hussain</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af27"><institution>University of Michigan Comprehensive Cancer Center</institution>,<addr-line>Ann Arbor</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="James, N D" sort="James, N D" uniqKey="James N" first="N. D." last="James">N. D. James</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af20"><addr-line>Cancer Research Centre</addr-line>,<institution>University of Warwick</institution>,<addr-line>Warwick</addr-line>,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="mdv257_af28"><addr-line>Queen Elizabeth Hospital Birmingham</addr-line>,<institution>University Hospitals Birmingham</institution>,<addr-line>Birmingham</addr-line>,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lecouvet, F E" sort="Lecouvet, F E" uniqKey="Lecouvet F" first="F. E." last="Lecouvet">F. E. Lecouvet</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af29"><addr-line>Department of Radiology, Centre du Cancer et Institut de Recherche Expérimentale et Clinique (IREC)</addr-line>,<institution>Cliniques Universitaires Saint Luc</institution>,<addr-line>Brussels</addr-line>,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Logothetis, C J" sort="Logothetis, C J" uniqKey="Logothetis C" first="C. J." last="Logothetis">C. J. Logothetis</name><affiliation><nlm:aff id="mdv257_af3"><addr-line>Department of Genitourinary Medical Oncology</addr-line>,<institution>MD Anderson Cancer Centre</institution>,<addr-line>Houston</addr-line></nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="mdv257_af4"><addr-line>Department of Genitourinary Medical Oncology, David H. Koch Centre</addr-line>,<institution>The University of Texas M. D. Anderson Cancer Centre</institution>,<addr-line>Houston</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Mastris, K" sort="Mastris, K" uniqKey="Mastris K" first="K." last="Mastris">K. Mastris</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af30"><institution>Europa Uomo Prostate Patients</institution>,<addr-line>Clayhall Ilford</addr-line>,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Nilsson, S" sort="Nilsson, S" uniqKey="Nilsson S" first="S." last="Nilsson">S. Nilsson</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af31"><addr-line>Department of Oncology-Pathology</addr-line>,<institution>Karolinska Institutet</institution>,<addr-line>Stockholm</addr-line>,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Oh, W K" sort="Oh, W K" uniqKey="Oh W" first="W. K." last="Oh">W. K. Oh</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af32"><addr-line>Division of Haematology and Medical Oncology</addr-line>,<institution>The Tisch Cancer Institute</institution>,<institution>Icahn School of Medicine at Mount Sinai</institution>,<addr-line>New York</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Olmos, D" sort="Olmos, D" uniqKey="Olmos D" first="D." last="Olmos">D. Olmos</name><affiliation><nlm:aff id="mdv257_af33"><institution>Prostate Cancer Clinical Research Unit, Spanish National Cancer Research Centre (CNIO)</institution>,<addr-line>Madrid</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="mdv257_af34"><institution>CNIO-IBIMA Genitourinary Cancer Unit, Hospitales Universitarios Virgen de la Victoria y Regional de Málaga, Málaga</institution></nlm:aff></affiliation><affiliation><nlm:aff id="mdv257_af35"><institution>Centro Integral Oncológico Clara Campal (CIOCC), Madrid, Spain</institution></nlm:aff></affiliation></author><author><name sortKey="Padhani, A R" sort="Padhani, A R" uniqKey="Padhani A" first="A. R." last="Padhani">A. R. Padhani</name><affiliation><nlm:aff id="mdv257_af36"><institution>Paul Strickland Scanner Centre, Mount Vernon Cancer Centre</institution>,<addr-line>Northwood</addr-line></nlm:aff></affiliation></author><author><name sortKey="Parker, C" sort="Parker, C" uniqKey="Parker C" first="C." last="Parker">C. Parker</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af37"><addr-line>Prostate Cancer Targeted Therapy Group, Academic Urology Unit and Department of Diagnostic Radiology</addr-line>,<institution>The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research</institution>,<addr-line>Sutton</addr-line>,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Rubin, M A" sort="Rubin, M A" uniqKey="Rubin M" first="M. A." last="Rubin">M. A. Rubin</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af38"><addr-line>Institute for Precision Medicine, Meyer Cancer Center, Department of Pathology and Urology</addr-line>,<institution>Weill Cornell Medical College and NewYork Presbyterian</institution>,<addr-line>New York</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Schalken, J A" sort="Schalken, J A" uniqKey="Schalken J" first="J. A." last="Schalken">J. A. Schalken</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af39"><addr-line>Department of Urology</addr-line>,<institution>Radboud University, Medical Centre</institution>,<addr-line>Nijmegen</addr-line>,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Scher, H I" sort="Scher, H I" uniqKey="Scher H" first="H. I." last="Scher">H. I. Scher</name><affiliation><nlm:aff id="mdv257_af14"><addr-line>Department of Medicine</addr-line>,<institution>Weill Cornell Medical College</institution>,<addr-line>New York</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="mdv257_af40"><addr-line>Genitourinary Oncology Service, Department of Medicine</addr-line>,<institution>Memorial Sloan Kettering Cancer Centre</institution>,<addr-line>New York</addr-line></nlm:aff></affiliation></author><author><name sortKey="Sella, A" sort="Sella, A" uniqKey="Sella A" first="A." last="Sella">A. Sella</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af41"><addr-line>Department of Oncology, Assaf Harofeh Medical Centre</addr-line>,<institution>Tel-Aviv University, Sackler School of Medicine</institution>,<addr-line>Zerifin</addr-line>,<country>Israel</country></nlm:aff><country xml:lang="fr">Israël</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Shore, N D" sort="Shore, N D" uniqKey="Shore N" first="N. D." last="Shore">N. D. Shore</name><affiliation><nlm:aff id="mdv257_af42"><addr-line>Department of Urology</addr-line>,<institution>Carolina Urologic Research Centre</institution>,<addr-line>Myrtle Beach</addr-line></nlm:aff></affiliation></author><author><name sortKey="Small, E J" sort="Small, E J" uniqKey="Small E" first="E. J." last="Small">E. J. Small</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af43"><addr-line>Helen Diller Family Comprehensive Cancer Centre</addr-line>,<institution>UCSF</institution>,<addr-line>San Francisco</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Sternberg, C N" sort="Sternberg, C N" uniqKey="Sternberg C" first="C. N." last="Sternberg">C. N. Sternberg</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af44"><addr-line>Department of Medical Oncology</addr-line>,<institution>San Camillo and Forlanini Hospitals</institution>,<addr-line>Rome</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Suzuki, H" sort="Suzuki, H" uniqKey="Suzuki H" first="H." last="Suzuki">H. Suzuki</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af45"><addr-line>Department of Urology</addr-line>,<institution>Toho University Sakura Medical Center</institution>,<addr-line>Chiba</addr-line>,<country>Japan</country></nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Sweeney, C J" sort="Sweeney, C J" uniqKey="Sweeney C" first="C. J." last="Sweeney">C. J. Sweeney</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af46"><addr-line>Department of Medical Oncology</addr-line>,<institution>Dana-Farber Cancer Institute and Brigham and Women's Hospital</institution>,<institution>Harvard Medical School</institution>,<addr-line>Boston</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Tannock, I F" sort="Tannock, I F" uniqKey="Tannock I" first="I. F." last="Tannock">I. F. Tannock</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af47"><addr-line>Department of Medical Oncology and Haematology</addr-line>,<institution>Princess Margaret Cancer Centre</institution>,<addr-line>Toronto</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Tombal, B" sort="Tombal, B" uniqKey="Tombal B" first="B." last="Tombal">B. Tombal</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af48"><addr-line>Service D'Urologie, Institut de Recherche Clinique</addr-line>,<institution>Université Catholique de Louvain</institution>,<addr-line>Brussels</addr-line>,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26041764</idno><idno type="pmc">4511225</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511225</idno><idno type="RBID">PMC:4511225</idno><idno type="doi">10.1093/annonc/mdv257</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000247</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000247</idno><idno type="wicri:Area/Pmc/Curation">000247</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000247</idno><idno type="wicri:Area/Pmc/Checkpoint">000E72</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000E72</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">002A66</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002A66</idno><idno type="wicri:Area/PubMed/Curation">002996</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002996</idno><idno type="wicri:Area/PubMed/Checkpoint">002996</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002996</idno><idno type="wicri:Area/Ncbi/Merge">002664</idno><idno type="wicri:Area/Ncbi/Curation">002664</idno><idno type="wicri:Area/Ncbi/Checkpoint">002664</idno><idno type="wicri:doubleKey">0923-7534:2015:Gillessen S:management:of:patients</idno><idno type="wicri:Area/Main/Merge">002B63</idno><idno type="wicri:Area/Main/Curation">002B63</idno><idno type="wicri:Area/Main/Exploration">002B63</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015</title><author><name sortKey="Gillessen, S" sort="Gillessen, S" uniqKey="Gillessen S" first="S." last="Gillessen">S. Gillessen</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af1"><addr-line>Department of Oncology/Haematology</addr-line>,<institution>Kantonsspital St Gallen</institution>,<addr-line>St Gallen</addr-line>,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Omlin, A" sort="Omlin, A" uniqKey="Omlin A" first="A." last="Omlin">A. Omlin</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af1"><addr-line>Department of Oncology/Haematology</addr-line>,<institution>Kantonsspital St Gallen</institution>,<addr-line>St Gallen</addr-line>,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Attard, G" sort="Attard, G" uniqKey="Attard G" first="G." last="Attard">G. Attard</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af2"><addr-line>Prostate Cancer Targeted Therapy Group and Drug Development Unit</addr-line>,<institution>The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research</institution>,<addr-line>Sutton</addr-line>,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="De Bono, J S" sort="De Bono, J S" uniqKey="De Bono J" first="J. S." last="De Bono">J. S. De Bono</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af2"><addr-line>Prostate Cancer Targeted Therapy Group and Drug Development Unit</addr-line>,<institution>The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research</institution>,<addr-line>Sutton</addr-line>,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Efstathiou, E" sort="Efstathiou, E" uniqKey="Efstathiou E" first="E." last="Efstathiou">E. Efstathiou</name><affiliation><nlm:aff id="mdv257_af3"><addr-line>Department of Genitourinary Medical Oncology</addr-line>,<institution>MD Anderson Cancer Centre</institution>,<addr-line>Houston</addr-line></nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="mdv257_af4"><addr-line>Department of Genitourinary Medical Oncology, David H. Koch Centre</addr-line>,<institution>The University of Texas M. D. Anderson Cancer Centre</institution>,<addr-line>Houston</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="mdv257_af5"><addr-line>Department of Clinical Therapeutics</addr-line>,<institution>Alexandra Hospital, National and Kapodistrian University of Athens Medical School</institution>,<addr-line>Athens</addr-line>,<country>Greece</country></nlm:aff><country xml:lang="fr">Grèce</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Fizazi, K" sort="Fizazi, K" uniqKey="Fizazi K" first="K." last="Fizazi">K. Fizazi</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af6"><addr-line>Department of Cancer Medicine, Institut Gustave Roussy</addr-line>,<institution>University of Paris Sud</institution>,<addr-line>Villejuif</addr-line>,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Halabi, S" sort="Halabi, S" uniqKey="Halabi S" first="S." last="Halabi">S. Halabi</name><affiliation><nlm:aff id="mdv257_af7"><addr-line>Department of Biostatistics and Bioinformatics</addr-line>,<institution>Duke University</institution>,<addr-line>Durham</addr-line></nlm:aff></affiliation></author><author><name sortKey="Nelson, P S" sort="Nelson, P S" uniqKey="Nelson P" first="P. S." last="Nelson">P. S. Nelson</name><affiliation><nlm:aff id="mdv257_af8"><addr-line>Division of Human Biology</addr-line>,<institution>Fred Hutchinson Cancer Research Centre</institution>,<addr-line>Seattle</addr-line></nlm:aff></affiliation></author><author><name sortKey="Sartor, O" sort="Sartor, O" uniqKey="Sartor O" first="O." last="Sartor">O. Sartor</name><affiliation><nlm:aff id="mdv257_af9"><addr-line>Tulane Cancer Centre</addr-line>,<institution>Tulane University</institution>,<addr-line>New Orleans</addr-line></nlm:aff></affiliation></author><author><name sortKey="Smith, M R" sort="Smith, M R" uniqKey="Smith M" first="M. R." last="Smith">M. R. Smith</name><affiliation><nlm:aff id="mdv257_af10"><institution>Massachusetts General Hospital Cancer Centre</institution>,<addr-line>Boston</addr-line></nlm:aff></affiliation></author><author><name sortKey="Soule, H R" sort="Soule, H R" uniqKey="Soule H" first="H. R." last="Soule">H. R. Soule</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af11"><institution>Prostate Cancer Foundation</institution>,<addr-line>Santa Monica</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Akaza, H" sort="Akaza, H" uniqKey="Akaza H" first="H." last="Akaza">H. Akaza</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af12"><addr-line>Research Centre for Advanced Science and Technology</addr-line>,<institution>The University of Tokyo</institution>,<addr-line>Tokyo</addr-line>,<country>Japan</country></nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Beer, T M" sort="Beer, T M" uniqKey="Beer T" first="T. M." last="Beer">T. M. Beer</name><affiliation><nlm:aff id="mdv257_af13"><institution>Oregon Health & Science University Knight Cancer Institute</institution>,<addr-line>Portland</addr-line></nlm:aff></affiliation></author><author><name sortKey="Beltran, H" sort="Beltran, H" uniqKey="Beltran H" first="H." last="Beltran">H. Beltran</name><affiliation><nlm:aff id="mdv257_af14"><addr-line>Department of Medicine</addr-line>,<institution>Weill Cornell Medical College</institution>,<addr-line>New York</addr-line></nlm:aff></affiliation></author><author><name sortKey="Chinnaiyan, A M" sort="Chinnaiyan, A M" uniqKey="Chinnaiyan A" first="A. M." last="Chinnaiyan">A. M. Chinnaiyan</name><affiliation><nlm:aff id="mdv257_af15"><addr-line>Michigan Centre for Translational Pathology, Department of Pathology</addr-line></nlm:aff><wicri:noCountry code="subfield">Department of Pathology</wicri:noCountry></affiliation><affiliation><nlm:aff id="mdv257_af16"><addr-line>Department of Urology, Comprehensive Cancer Centre</addr-line></nlm:aff><wicri:noCountry code="subfield">Comprehensive Cancer Centre</wicri:noCountry></affiliation><affiliation wicri:level="1"><nlm:aff id="mdv257_af17"><addr-line>Howard Hughes Medical Institute</addr-line>,<institution>University of Michigan Medical School</institution>,<addr-line>Ann Arbor</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Daugaard, G" sort="Daugaard, G" uniqKey="Daugaard G" first="G." last="Daugaard">G. Daugaard</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af18"><addr-line>Department of Oncology</addr-line>,<institution>Copenhagen University Hospital, Rigshospitalet</institution>,<addr-line>Copenhagen</addr-line>,<country>Denmark</country></nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Davis, I D" sort="Davis, I D" uniqKey="Davis I" first="I. D." last="Davis">I. D. Davis</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af19"><addr-line>Monash University and Eastern Health</addr-line>,<institution>Eastern Health Clinical School</institution>,<addr-line>Box Hill</addr-line>,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="De Santis, M" sort="De Santis, M" uniqKey="De Santis M" first="M." last="De Santis">M. De Santis</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af20"><addr-line>Cancer Research Centre</addr-line>,<institution>University of Warwick</institution>,<addr-line>Warwick</addr-line>,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="mdv257_af21"><institution>Ludwig Boltzmann Institute for Applied Cancer Research, Kaiser Franz Josef-Spital</institution>,<addr-line>Vienna</addr-line>,<country>Austria</country></nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Drake, C G" sort="Drake, C G" uniqKey="Drake C" first="C. G." last="Drake">C. G. Drake</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af22"><addr-line>Johns Hopkins Sidney Kimmel Cancer Center and The Brady Urological Institute, Department of Urology</addr-line>,<institution>Johns Hopkins University School of Medicine</institution>,<addr-line>Baltimore</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Eeles, R A" sort="Eeles, R A" uniqKey="Eeles R" first="R. A." last="Eeles">R. A. Eeles</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af23"><institution>The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust</institution>,<addr-line>London</addr-line>,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Fanti, S" sort="Fanti, S" uniqKey="Fanti S" first="S." last="Fanti">S. Fanti</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af24"><addr-line>Department of Nuclear Medicine, Policlinico S. Orsola</addr-line>,<institution>University of Bologna</institution>,<addr-line>Bologna</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gleave, M E" sort="Gleave, M E" uniqKey="Gleave M" first="M. E." last="Gleave">M. E. Gleave</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af25"><addr-line>Urological Sciences, Vancouver Prostate Centre</addr-line>,<institution>University of British Columbia</institution>,<addr-line>Vancouver</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Heidenreich, A" sort="Heidenreich, A" uniqKey="Heidenreich A" first="A." last="Heidenreich">A. Heidenreich</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af26"><addr-line>Klinik und Poliklinik für Urologie</addr-line>,<institution>RWTH University Aachen</institution>,<addr-line>Aachen</addr-line>,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hussain, M" sort="Hussain, M" uniqKey="Hussain M" first="M." last="Hussain">M. Hussain</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af27"><institution>University of Michigan Comprehensive Cancer Center</institution>,<addr-line>Ann Arbor</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="James, N D" sort="James, N D" uniqKey="James N" first="N. D." last="James">N. D. James</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af20"><addr-line>Cancer Research Centre</addr-line>,<institution>University of Warwick</institution>,<addr-line>Warwick</addr-line>,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="mdv257_af28"><addr-line>Queen Elizabeth Hospital Birmingham</addr-line>,<institution>University Hospitals Birmingham</institution>,<addr-line>Birmingham</addr-line>,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lecouvet, F E" sort="Lecouvet, F E" uniqKey="Lecouvet F" first="F. E." last="Lecouvet">F. E. Lecouvet</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af29"><addr-line>Department of Radiology, Centre du Cancer et Institut de Recherche Expérimentale et Clinique (IREC)</addr-line>,<institution>Cliniques Universitaires Saint Luc</institution>,<addr-line>Brussels</addr-line>,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Logothetis, C J" sort="Logothetis, C J" uniqKey="Logothetis C" first="C. J." last="Logothetis">C. J. Logothetis</name><affiliation><nlm:aff id="mdv257_af3"><addr-line>Department of Genitourinary Medical Oncology</addr-line>,<institution>MD Anderson Cancer Centre</institution>,<addr-line>Houston</addr-line></nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="mdv257_af4"><addr-line>Department of Genitourinary Medical Oncology, David H. Koch Centre</addr-line>,<institution>The University of Texas M. D. Anderson Cancer Centre</institution>,<addr-line>Houston</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Mastris, K" sort="Mastris, K" uniqKey="Mastris K" first="K." last="Mastris">K. Mastris</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af30"><institution>Europa Uomo Prostate Patients</institution>,<addr-line>Clayhall Ilford</addr-line>,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Nilsson, S" sort="Nilsson, S" uniqKey="Nilsson S" first="S." last="Nilsson">S. Nilsson</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af31"><addr-line>Department of Oncology-Pathology</addr-line>,<institution>Karolinska Institutet</institution>,<addr-line>Stockholm</addr-line>,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Oh, W K" sort="Oh, W K" uniqKey="Oh W" first="W. K." last="Oh">W. K. Oh</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af32"><addr-line>Division of Haematology and Medical Oncology</addr-line>,<institution>The Tisch Cancer Institute</institution>,<institution>Icahn School of Medicine at Mount Sinai</institution>,<addr-line>New York</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Olmos, D" sort="Olmos, D" uniqKey="Olmos D" first="D." last="Olmos">D. Olmos</name><affiliation><nlm:aff id="mdv257_af33"><institution>Prostate Cancer Clinical Research Unit, Spanish National Cancer Research Centre (CNIO)</institution>,<addr-line>Madrid</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="mdv257_af34"><institution>CNIO-IBIMA Genitourinary Cancer Unit, Hospitales Universitarios Virgen de la Victoria y Regional de Málaga, Málaga</institution></nlm:aff></affiliation><affiliation><nlm:aff id="mdv257_af35"><institution>Centro Integral Oncológico Clara Campal (CIOCC), Madrid, Spain</institution></nlm:aff></affiliation></author><author><name sortKey="Padhani, A R" sort="Padhani, A R" uniqKey="Padhani A" first="A. R." last="Padhani">A. R. Padhani</name><affiliation><nlm:aff id="mdv257_af36"><institution>Paul Strickland Scanner Centre, Mount Vernon Cancer Centre</institution>,<addr-line>Northwood</addr-line></nlm:aff></affiliation></author><author><name sortKey="Parker, C" sort="Parker, C" uniqKey="Parker C" first="C." last="Parker">C. Parker</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af37"><addr-line>Prostate Cancer Targeted Therapy Group, Academic Urology Unit and Department of Diagnostic Radiology</addr-line>,<institution>The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research</institution>,<addr-line>Sutton</addr-line>,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Rubin, M A" sort="Rubin, M A" uniqKey="Rubin M" first="M. A." last="Rubin">M. A. Rubin</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af38"><addr-line>Institute for Precision Medicine, Meyer Cancer Center, Department of Pathology and Urology</addr-line>,<institution>Weill Cornell Medical College and NewYork Presbyterian</institution>,<addr-line>New York</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Schalken, J A" sort="Schalken, J A" uniqKey="Schalken J" first="J. A." last="Schalken">J. A. Schalken</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af39"><addr-line>Department of Urology</addr-line>,<institution>Radboud University, Medical Centre</institution>,<addr-line>Nijmegen</addr-line>,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Scher, H I" sort="Scher, H I" uniqKey="Scher H" first="H. I." last="Scher">H. I. Scher</name><affiliation><nlm:aff id="mdv257_af14"><addr-line>Department of Medicine</addr-line>,<institution>Weill Cornell Medical College</institution>,<addr-line>New York</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="mdv257_af40"><addr-line>Genitourinary Oncology Service, Department of Medicine</addr-line>,<institution>Memorial Sloan Kettering Cancer Centre</institution>,<addr-line>New York</addr-line></nlm:aff></affiliation></author><author><name sortKey="Sella, A" sort="Sella, A" uniqKey="Sella A" first="A." last="Sella">A. Sella</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af41"><addr-line>Department of Oncology, Assaf Harofeh Medical Centre</addr-line>,<institution>Tel-Aviv University, Sackler School of Medicine</institution>,<addr-line>Zerifin</addr-line>,<country>Israel</country></nlm:aff><country xml:lang="fr">Israël</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Shore, N D" sort="Shore, N D" uniqKey="Shore N" first="N. D." last="Shore">N. D. Shore</name><affiliation><nlm:aff id="mdv257_af42"><addr-line>Department of Urology</addr-line>,<institution>Carolina Urologic Research Centre</institution>,<addr-line>Myrtle Beach</addr-line></nlm:aff></affiliation></author><author><name sortKey="Small, E J" sort="Small, E J" uniqKey="Small E" first="E. J." last="Small">E. J. Small</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af43"><addr-line>Helen Diller Family Comprehensive Cancer Centre</addr-line>,<institution>UCSF</institution>,<addr-line>San Francisco</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Sternberg, C N" sort="Sternberg, C N" uniqKey="Sternberg C" first="C. N." last="Sternberg">C. N. Sternberg</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af44"><addr-line>Department of Medical Oncology</addr-line>,<institution>San Camillo and Forlanini Hospitals</institution>,<addr-line>Rome</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Suzuki, H" sort="Suzuki, H" uniqKey="Suzuki H" first="H." last="Suzuki">H. Suzuki</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af45"><addr-line>Department of Urology</addr-line>,<institution>Toho University Sakura Medical Center</institution>,<addr-line>Chiba</addr-line>,<country>Japan</country></nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Sweeney, C J" sort="Sweeney, C J" uniqKey="Sweeney C" first="C. J." last="Sweeney">C. J. Sweeney</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af46"><addr-line>Department of Medical Oncology</addr-line>,<institution>Dana-Farber Cancer Institute and Brigham and Women's Hospital</institution>,<institution>Harvard Medical School</institution>,<addr-line>Boston</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Tannock, I F" sort="Tannock, I F" uniqKey="Tannock I" first="I. F." last="Tannock">I. F. Tannock</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af47"><addr-line>Department of Medical Oncology and Haematology</addr-line>,<institution>Princess Margaret Cancer Centre</institution>,<addr-line>Toronto</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Tombal, B" sort="Tombal, B" uniqKey="Tombal B" first="B." last="Tombal">B. Tombal</name><affiliation wicri:level="1"><nlm:aff id="mdv257_af48"><addr-line>Service D'Urologie, Institut de Recherche Clinique</addr-line>,<institution>Université Catholique de Louvain</institution>,<addr-line>Brussels</addr-line>,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Annals of Oncology</title><idno type="ISSN">0923-7534</idno><idno type="eISSN">1569-8041</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adenocarcinoma (pathology)</term><term>Adenocarcinoma (therapy)</term><term>Androgen Antagonists (therapeutic use)</term><term>Antineoplastic Agents (therapeutic use)</term><term>Antineoplastic Agents, Hormonal (therapeutic use)</term><term>Bone Density Conservation Agents (therapeutic use)</term><term>Humans</term><term>Male</term><term>Orchiectomy</term><term>Practice Guidelines as Topic</term><term>Prostatectomy</term><term>Prostatic Neoplasms (pathology)</term><term>Prostatic Neoplasms (therapy)</term><term>Prostatic Neoplasms, Castration-Resistant (pathology)</term><term>Prostatic Neoplasms, Castration-Resistant (therapy)</term><term>Radiotherapy, Adjuvant</term><term>Taxoids (therapeutic use)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adénocarcinome ()</term><term>Adénocarcinome (anatomopathologie)</term><term>Agents de maintien de la densité osseuse (usage thérapeutique)</term><term>Antagonistes des androgènes (usage thérapeutique)</term><term>Antinéoplasiques (usage thérapeutique)</term><term>Antinéoplasiques hormonaux (usage thérapeutique)</term><term>Guides de bonnes pratiques cliniques comme sujet</term><term>Humains</term><term>Mâle</term><term>Orchidectomie</term><term>Prostatectomie</term><term>Radiothérapie adjuvante</term><term>Taxoïdes (usage thérapeutique)</term><term>Tumeurs de la prostate ()</term><term>Tumeurs de la prostate (anatomopathologie)</term><term>Tumeurs prostatiques résistantes à la castration ()</term><term>Tumeurs prostatiques résistantes à la castration (anatomopathologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Androgen Antagonists</term><term>Antineoplastic Agents</term><term>Antineoplastic Agents, Hormonal</term><term>Bone Density Conservation Agents</term><term>Taxoids</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Adénocarcinome</term><term>Tumeurs de la prostate</term><term>Tumeurs prostatiques résistantes à la castration</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Adenocarcinoma</term><term>Prostatic Neoplasms</term><term>Prostatic Neoplasms, Castration-Resistant</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Adenocarcinoma</term><term>Prostatic Neoplasms</term><term>Prostatic Neoplasms, Castration-Resistant</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Agents de maintien de la densité osseuse</term><term>Antagonistes des androgènes</term><term>Antinéoplasiques</term><term>Antinéoplasiques hormonaux</term><term>Taxoïdes</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Male</term><term>Orchiectomy</term><term>Practice Guidelines as Topic</term><term>Prostatectomy</term><term>Radiotherapy, Adjuvant</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adénocarcinome</term><term>Guides de bonnes pratiques cliniques comme sujet</term><term>Humains</term><term>Mâle</term><term>Orchidectomie</term><term>Prostatectomie</term><term>Radiothérapie adjuvante</term><term>Tumeurs de la prostate</term><term>Tumeurs prostatiques résistantes à la castration</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The first St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) Expert Panel identified and reviewed available evidence for the ten most important areas of controversy in advanced prostate cancer management. Recommendations based on expert opinion are presented. Detailed decisions on treatment will involve clinical consideration of disease extent and location, prior treatments, host factors, patient preferences and logistical and economic constraints.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="De Bono, Js" uniqKey="De Bono J">JS de Bono</name></author><author><name sortKey="Oudard, S" uniqKey="Oudard S">S Oudard</name></author><author><name sortKey="Ozguroglu, M" uniqKey="Ozguroglu M">M Ozguroglu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kantoff, Pw" uniqKey="Kantoff P">PW Kantoff</name></author><author><name sortKey="Higano, Cs" uniqKey="Higano C">CS Higano</name></author><author><name sortKey="Shore, Nd" uniqKey="Shore N">ND Shore</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Bono, Js" uniqKey="De Bono J">JS de Bono</name></author><author><name sortKey="Logothetis, Cj" uniqKey="Logothetis C">CJ 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Guttilla</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bayley, A" uniqKey="Bayley A">A Bayley</name></author><author><name sortKey="Milosevic, M" uniqKey="Milosevic M">M Milosevic</name></author><author><name sortKey="Blend, R" uniqKey="Blend R">R Blend</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Venkitaraman, R" uniqKey="Venkitaraman R">R Venkitaraman</name></author><author><name sortKey="Sohaib, Sa" uniqKey="Sohaib S">SA Sohaib</name></author><author><name sortKey="Barbachano, Y" uniqKey="Barbachano Y">Y Barbachano</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thuret, R" uniqKey="Thuret R">R Thuret</name></author><author><name sortKey="Massard, C" uniqKey="Massard C">C Massard</name></author><author><name sortKey="Gross Goupil, M" uniqKey="Gross Goupil M">M Gross-Goupil</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Angelergues, A" uniqKey="Angelergues A">A Angelergues</name></author><author><name sortKey="Maillet, D" uniqKey="Maillet D">D Maillet</name></author><author><name sortKey="Flechon, A" uniqKey="Flechon A">A Flechon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Burgio, Sl" uniqKey="Burgio S">SL Burgio</name></author><author><name sortKey="Conteduca, V" uniqKey="Conteduca V">V Conteduca</name></author><author><name sortKey="Rudnas, B" uniqKey="Rudnas B">B Rudnas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tombal, B" uniqKey="Tombal B">B Tombal</name></author><author><name sortKey="Rezazadeh, A" uniqKey="Rezazadeh A">A Rezazadeh</name></author><author><name sortKey="Therasse, P" uniqKey="Therasse P">P Therasse</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lecouvet, Fe" uniqKey="Lecouvet F">FE Lecouvet</name></author><author><name sortKey="Larbi, A" uniqKey="Larbi A">A Larbi</name></author><author><name sortKey="Pasoglou, V" uniqKey="Pasoglou V">V Pasoglou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Blackledge, Md" uniqKey="Blackledge M">MD Blackledge</name></author><author><name sortKey="Collins, Dj" uniqKey="Collins D">DJ Collins</name></author><author><name sortKey="Tunariu, N" uniqKey="Tunariu N">N Tunariu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Padhani, Ar" uniqKey="Padhani A">AR Padhani</name></author><author><name sortKey="Makris, A" uniqKey="Makris A">A Makris</name></author><author><name sortKey="Gall, P" uniqKey="Gall P">P Gall</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fizazi, K" uniqKey="Fizazi K">K Fizazi</name></author><author><name sortKey="Carducci, M" uniqKey="Carducci M">M Carducci</name></author><author><name sortKey="Smith, M" uniqKey="Smith M">M Smith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Logothetis, Cj" uniqKey="Logothetis C">CJ Logothetis</name></author><author><name sortKey="Basch, E" uniqKey="Basch E">E Basch</name></author><author><name sortKey="Molina, A" uniqKey="Molina A">A Molina</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fizazi, K" uniqKey="Fizazi K">K Fizazi</name></author><author><name sortKey="Scher, Hi" uniqKey="Scher H">HI Scher</name></author><author><name sortKey="Miller, K" uniqKey="Miller K">K Miller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sartor, O" uniqKey="Sartor O">O Sartor</name></author><author><name sortKey="Coleman, R" uniqKey="Coleman R">R Coleman</name></author><author><name sortKey="Nilsson, S" uniqKey="Nilsson S">S Nilsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Spritzer, Ce" uniqKey="Spritzer C">CE Spritzer</name></author><author><name sortKey="Afonso, Pd" uniqKey="Afonso P">PD Afonso</name></author><author><name sortKey="Vinson, En" uniqKey="Vinson E">EN Vinson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Efstathiou, E" uniqKey="Efstathiou E">E Efstathiou</name></author><author><name sortKey="Titus, M" uniqKey="Titus M">M Titus</name></author><author><name sortKey="Tsavachidou, D" uniqKey="Tsavachidou D">D Tsavachidou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Efstathiou, E" uniqKey="Efstathiou E">E Efstathiou</name></author><author><name sortKey="Titus, M" uniqKey="Titus M">M Titus</name></author><author><name sortKey="Wen, S" uniqKey="Wen S">S Wen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ferraldeschi, R" uniqKey="Ferraldeschi R">R Ferraldeschi</name></author><author><name sortKey="Nava Rodrigues, D" uniqKey="Nava Rodrigues D">D Nava Rodrigues</name></author><author><name sortKey="Riisnaes, R" uniqKey="Riisnaes R">R Riisnaes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Allen, Em" uniqKey="Van Allen E">EM Van Allen</name></author><author><name sortKey="Foye, A" uniqKey="Foye A">A Foye</name></author><author><name sortKey="Wagle, N" uniqKey="Wagle N">N Wagle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Beltran, H" uniqKey="Beltran H">H Beltran</name></author><author><name sortKey="Tomlins, S" uniqKey="Tomlins S">S Tomlins</name></author><author><name sortKey="Aparicio, A" uniqKey="Aparicio A">A Aparicio</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Autriche</li><li>Belgique</li><li>Canada</li><li>Danemark</li><li>France</li><li>Grèce</li><li>Israël</li><li>Italie</li><li>Japon</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Suisse</li><li>Suède</li><li>États-Unis</li></country></list><tree><noCountry><name sortKey="Beer, T M" sort="Beer, T M" uniqKey="Beer T" first="T. M." last="Beer">T. M. Beer</name><name sortKey="Beltran, H" sort="Beltran, H" uniqKey="Beltran H" first="H." last="Beltran">H. Beltran</name><name sortKey="Halabi, S" sort="Halabi, S" uniqKey="Halabi S" first="S." last="Halabi">S. Halabi</name><name sortKey="Nelson, P S" sort="Nelson, P S" uniqKey="Nelson P" first="P. S." last="Nelson">P. S. Nelson</name><name sortKey="Olmos, D" sort="Olmos, D" uniqKey="Olmos D" first="D." last="Olmos">D. Olmos</name><name sortKey="Padhani, A R" sort="Padhani, A R" uniqKey="Padhani A" first="A. R." last="Padhani">A. R. Padhani</name><name sortKey="Sartor, O" sort="Sartor, O" uniqKey="Sartor O" first="O." last="Sartor">O. Sartor</name><name sortKey="Scher, H I" sort="Scher, H I" uniqKey="Scher H" first="H. I." last="Scher">H. I. Scher</name><name sortKey="Shore, N D" sort="Shore, N D" uniqKey="Shore N" first="N. D." last="Shore">N. D. Shore</name><name sortKey="Smith, M R" sort="Smith, M R" uniqKey="Smith M" first="M. R." last="Smith">M. R. 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Oh</name><name sortKey="Rubin, M A" sort="Rubin, M A" uniqKey="Rubin M" first="M. A." last="Rubin">M. A. Rubin</name><name sortKey="Small, E J" sort="Small, E J" uniqKey="Small E" first="E. J." last="Small">E. J. Small</name><name sortKey="Soule, H R" sort="Soule, H R" uniqKey="Soule H" first="H. R." last="Soule">H. R. Soule</name><name sortKey="Sweeney, C J" sort="Sweeney, C J" uniqKey="Sweeney C" first="C. J." last="Sweeney">C. J. Sweeney</name></country><country name="Grèce"><noRegion><name sortKey="Efstathiou, E" sort="Efstathiou, E" uniqKey="Efstathiou E" first="E." last="Efstathiou">E. Efstathiou</name></noRegion></country><country name="France"><noRegion><name sortKey="Fizazi, K" sort="Fizazi, K" uniqKey="Fizazi K" first="K." last="Fizazi">K. Fizazi</name></noRegion></country><country name="Japon"><noRegion><name sortKey="Akaza, H" sort="Akaza, H" uniqKey="Akaza H" first="H." last="Akaza">H. 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Sternberg</name></country><country name="Canada"><noRegion><name sortKey="Gleave, M E" sort="Gleave, M E" uniqKey="Gleave M" first="M. E." last="Gleave">M. E. Gleave</name></noRegion><name sortKey="Tannock, I F" sort="Tannock, I F" uniqKey="Tannock I" first="I. F." last="Tannock">I. F. Tannock</name></country><country name="Allemagne"><noRegion><name sortKey="Heidenreich, A" sort="Heidenreich, A" uniqKey="Heidenreich A" first="A." last="Heidenreich">A. Heidenreich</name></noRegion></country><country name="Belgique"><noRegion><name sortKey="Lecouvet, F E" sort="Lecouvet, F E" uniqKey="Lecouvet F" first="F. E." last="Lecouvet">F. E. Lecouvet</name></noRegion><name sortKey="Tombal, B" sort="Tombal, B" uniqKey="Tombal B" first="B." last="Tombal">B. Tombal</name></country><country name="Suède"><noRegion><name sortKey="Nilsson, S" sort="Nilsson, S" uniqKey="Nilsson S" first="S." last="Nilsson">S. Nilsson</name></noRegion></country><country name="Pays-Bas"><noRegion><name sortKey="Schalken, J A" sort="Schalken, J A" uniqKey="Schalken J" first="J. A." last="Schalken">J. A. Schalken</name></noRegion></country><country name="Israël"><noRegion><name sortKey="Sella, A" sort="Sella, A" uniqKey="Sella A" first="A." last="Sella">A. Sella</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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